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Amorphous alumina nanowire arrays

Amorphous alumina nanowire arrays
We sought to explore the applicability of alumina for the presentation of a tetrapeptide directly into the cytosol to induce a phenotypic response from DC 2.4 cells.

N-Doped TiO2-Hybridized Graphene for Water Treatment

N-Doped TiO2-Hybridized Graphene for Water Treatment
Simple liquid doping and large scalable production of a N-doped TiO2/graphene photocatalyst shows great promise for wastewater treatment.

Magnetite Nanoparticle-Decorated Diatom Frustules

Magnetite Nanoparticle-Decorated Diatom Frustules
Our findings suggest that the diatom Pinnularia sp. frustule combines short-range periodicity and long-range isotropy for the wavelength-selective and angle-independent reflection of light.
Dr. Jiao’s current research is focused on the development of nanofabrication techniques for the property-controlled growth of nanotubes and nanowires, and the investigation of carbon nanotubes and semiconductor nanowires as building blocks for nanoelectronic devices and as the new generation of electron field emitters.

Dr. Jiao is committed to mentoring and developing new reseachers. In addition to managing an REU site, Dr. Jiao's lab provides a wide range of opportunities for both graduate and undergraduate research. Some of the projects currently under way are:

  • Nanoparticulate Adjuvants and Delivery Systems Towards New Generation Vaccines: Vaccination has greatly impacted global public health by controlling and preventing infectious diseases and treating cancers. However, it remains difficult to generate sufficient immunity with vaccines containing insufficient immunogenic antigens. To amplify the interaction between antigens and the immune system, we recently reported that antigen coupled to alumina nanoparticles is 500 times more efficiently processed by dendritic cells for major histocompatibility complex (MHC) class I antigen presentation, and elicits strong cytotoxic T cell response against cancer in vivo (Nature Nanotechnology, 2011, 6,645-50). We now extend these studies to infectious disease, with the goal of utilizing alumina NPs to elicit cytotoxic T cell response to defined pathogen antigens. Current student researchers: Kavita Meduri (graduate), Shree C. Aier (undergraduate); previous student researcher: Lester Lampert (graduate)

See the list of publications for more information about past projects.